Objectives: The aim of this work to measure if peripheral eosinophilia and total immunoglobulin E "IgE" levels correlate with the severity of chronic rhinosinusitis (CRS) proved by computed tomography (CT) scans of paranasal sinuses.
Study Design: Retrospective study from 30 patients with chronic rhinosinusitits (CRS).
Methods: CT scans were performed for all patients with CRS and peripheral eosinophilia and total IgE levels were measured. The relationship between peripheral eosinophilia and total IgE levels regarding their effect on severity of CRS.
Results: There was a significant positive correlation between peripheral eosinophilia and severity CRS. The total IgE levels did not correlate with the severity and mucosal disease of CRS.
Conclusion: Peripheral eosinophilia in patients with CRS indicates the severity and degree of mucosal affection guided by CT scans. In contrast, total IgE levels did not correlate with the severity of CRS and C.T scans findings.
Keywords: Eosinophilia, Immunoglobulin E "IgE", chronic rhinosinusitis.